Diagnosis and treatment of brain metastases from solid tumors: Guidelines from the European Association of neuro-oncology (EANO)
Soffietti R, Abacioglu U, Baumert B, Combs SE, Kinhult S, Kros JM, Marosi C, Metellus P, Radbruch A, Freixa SSV, Brada M, Carapella CM, Preusser M, Le Rhun E, Ruda R, Tonn JC, Weber DC, Weller M (2017)
Publication Type: Journal article
Publication year: 2017
Journal
Book Volume: 19
Pages Range: 162-174
Journal Issue: 2
Abstract
The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.
Involved external institutions
University of Turin / Università degli Studi di Torino (UNITO)
Italy (IT)
Neolife Medical Center
Turkey (TR)
MEDICLIN Robert Janker Klinik
Germany (DE)
Skåne University Hospital / Skånes universitetssjukhus
Sweden (SE)
Erasmus University Medical Center (MC)
Netherlands (NL)
Medizinische Universität Wien
Austria (AT)
Deutsches Krebsforschungszentrum (DKFZ)
Germany (DE)
Hospital Universitari Germans Trias i Pujol
Spain (ES)
The University of Liverpool
United Kingdom (GB)
Istituto Nazionale Tumori Regina Elena (IRE)
Italy (IT)
Universitätsklinikum Heidelberg
Germany (DE)
Ludwig-Maximilians-Universität (LMU)
Germany (DE)
Paul Scherrer Institute (PSI)
Switzerland (CH)
Universitätsspital Zürich (USZ)
Switzerland (CH)
Italy (IT)
Neolife Medical Center
Turkey (TR)
MEDICLIN Robert Janker Klinik
Germany (DE)
Skåne University Hospital / Skånes universitetssjukhus
Sweden (SE)
Erasmus University Medical Center (MC)
Netherlands (NL)
Medizinische Universität Wien
Austria (AT)
Deutsches Krebsforschungszentrum (DKFZ)
Germany (DE)
Hospital Universitari Germans Trias i Pujol
Spain (ES)
The University of Liverpool
United Kingdom (GB)
Istituto Nazionale Tumori Regina Elena (IRE)
Italy (IT)
Universitätsklinikum Heidelberg
Germany (DE)
Ludwig-Maximilians-Universität (LMU)
Germany (DE)
Paul Scherrer Institute (PSI)
Switzerland (CH)
Universitätsspital Zürich (USZ)
Switzerland (CH)
How to cite
APA:
Soffietti, R., Abacioglu, U., Baumert, B., Combs, S.E., Kinhult, S., Kros, J.M.,... Weller, M. (2017). Diagnosis and treatment of brain metastases from solid tumors: Guidelines from the European Association of neuro-oncology (EANO). Neuro-Oncology, 19(2), 162-174. https://doi.org/10.1093/neuonc/now241
MLA:
Soffietti, Riccardo, et al. "Diagnosis and treatment of brain metastases from solid tumors: Guidelines from the European Association of neuro-oncology (EANO)." Neuro-Oncology 19.2 (2017): 162-174.
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