Advances in Optoacoustic Neurotomography of Animal Models

Ovsepian SV, Olefir I, Ntziachristos V (2019)


Publication Type: Journal article, Review article

Publication year: 2019

Journal

Book Volume: 37

Pages Range: 1315-1326

Journal Issue: 12

DOI: 10.1016/j.tibtech.2019.07.012

Abstract

Unlike traditional optical methods, optoacoustic imaging is less sensitive to scattering of ballistic photons, so it is capable of high-resolution interrogation at a greater depth. By integrating video-rate visualization with multiplexing and sensing a range of endogenous and exogenous chromophores, optoacoustic imaging has matured into a versatile noninvasive investigation modality with rapidly expanding use in biomedical research. We review the principal features of the technology and discuss recent advances it has enabled in structural, functional, and molecular neuroimaging in small-animal models. In extending the boundaries of noninvasive observation beyond the reach of customary photonic methods, the latest developments in optoacoustics have substantially advanced neuroimaging inquiry, with promising implications for basic and translational studies.

Involved external institutions

How to cite

APA:

Ovsepian, S.V., Olefir, I., & Ntziachristos, V. (2019). Advances in Optoacoustic Neurotomography of Animal Models. Trends in Biotechnology, 37(12), 1315-1326. https://dx.doi.org/10.1016/j.tibtech.2019.07.012

MLA:

Ovsepian, Saak V., Ivan Olefir, and Vasilis Ntziachristos. "Advances in Optoacoustic Neurotomography of Animal Models." Trends in Biotechnology 37.12 (2019): 1315-1326.

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