Age-related craniofacial differences based on spatiooral face image atlases

Xavier IRR, Giraldi GA, Gibson SJ, Gattas GJF, Rueckert D, Thomaz CE (2019)

Publication Type: Journal article

Publication year: 2019

Journal

IET Image Processing Institution of Engineering and Technology (IET)

Book Volume: 13

Pages Range: 1561-1568

Journal Issue: 9

DOI: 10.1049/iet-ipr.2018.6271

Abstract

A number of studies have been developed recently in order to explore associations between craniofacial differences and genetics. Most of these works have been based on spatial face image models, adjusted for the counter effects of age. This approach provides a limited understanding of normal and abnormal craniofacial development owing to the lack of age progression information. Here, the authors propose and implement an imaging framework that combines facial landmark positioning, non-rigid registration, novel age-dependent face modelling and common distance metrics to disclose the most facial differences that vary across the time due to the subjects' age. All the experiments carried out and corresponding results presented here are based on a database comprising ordinary two-dimensional (2D) frontal face images of Down Syndrome (DS) and control sample groups. A number of craniofacial metrics have been successfully identified that highlight statistically significant and clinically relevant differences between the controls and the faces associated with DS within the age range from 1 to 18 years old, producing realistic unbiased face models with similar level of detail at all age-intervals, despite the small sample size available.

Involved external institutions

Centro Universitário da FEI BR Brazil (BR) National Laboratory of Scientific Computing / Laboratório Nacional de Computação Científica (LNCC) BR Brazil (BR) University of Kent GB United Kingdom (GB) University of São Paulo / Universidade de São Paulo (USP) BR Brazil (BR) Imperial College London / The Imperial College of Science, Technology and Medicine GB United Kingdom (GB)

How to cite

APA:

Xavier, I.R.R., Giraldi, G.A., Gibson, S.J., Gattas, G.J.F., Rueckert, D., & Thomaz, C.E. (2019). Age-related craniofacial differences based on spatiooral face image atlases. IET Image Processing, 13(9), 1561-1568. https://dx.doi.org/10.1049/iet-ipr.2018.6271

MLA:

Xavier, Igor R. R., et al. "Age-related craniofacial differences based on spatiooral face image atlases." IET Image Processing 13.9 (2019): 1561-1568.

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