Outcomes after complete dissolution of everolimus-eluting bioresorbable scaffolds implanted during routine practice Evolución de pacientes tratados con armazones coronarios bioabsorbibles liberadores de everolimus tras su disolución completa

Wiebe J, Hoppmann P, Cassese S, Rheude T, Colleran R, Kuna C, Rai H, Valeskini M, Ibrahim T, Joner M, Schunkert H, Laugwitz KL, Kastrati A, Byrne RA (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Revista Espanola De Cardiologia Elsevier España (Elsevier Doyma) / Sociedad Española de Cardiología

Book Volume: 74

Pages Range: 584-590

Journal Issue: 7

DOI: 10.1016/j.recesp.2020.06.041

Abstract

Introduction and objectives: Long-term outcomes of unselected patients treated with bioresorbable vascular scaffold (BVS) implantation are lacking, especially for the period after complete dissolution of the BVS. This study sought to evaluate 5-year outcomes in patients treated with BVS in routine practice. Methods: Consecutive patients who underwent implantation of everolimus-eluting BVS during routine clinical practice at 2 high-volume centres in Germany were studied. The patients were followed-up for up to 5 years. The primary endpoints of interest were the composite of death, myocardial infarction and target lesion revascularization, as well as definite scaffold thrombosis. Results: A total of 419 patients (mean age 66.6 ± 10.9 years; 31.5% had diabetes) were included, of whom 38.9% presented with an acute coronary syndrome. Of the 527 lesions treated, 49.0% were classified as complex and 13.1% were bifurcation lesions. At 5 years, the composite clinical endpoint occurred in 33.1% of patients and definite scaffold thrombosis occurred in 4.7%. Most definite scaffold thrombosis occurred within 2 years after BVS implantation. Conclusions: In patients treated with BVS implantation in routine clinical practice the rates of adverse clinical events at 5 years were high, including a considerable incidence of scaffold thrombosis.

Involved external institutions

Deutsches Herzzentrum München DE Germany (DE) Klinikum rechts der Isar DE Germany (DE) Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK e.V.) DE Germany (DE) Mater Private Hospital / Ospidéal Príobháideach an Mater IE Ireland (IE)

How to cite

APA:

Wiebe, J., Hoppmann, P., Cassese, S., Rheude, T., Colleran, R., Kuna, C.,... Byrne, R.A. (2021). Outcomes after complete dissolution of everolimus-eluting bioresorbable scaffolds implanted during routine practice Evolución de pacientes tratados con armazones coronarios bioabsorbibles liberadores de everolimus tras su disolución completa. Revista Espanola De Cardiologia, 74(7), 584-590. https://doi.org/10.1016/j.recesp.2020.06.041

MLA:

Wiebe, Jens, et al. "Outcomes after complete dissolution of everolimus-eluting bioresorbable scaffolds implanted during routine practice Evolución de pacientes tratados con armazones coronarios bioabsorbibles liberadores de everolimus tras su disolución completa." Revista Espanola De Cardiologia 74.7 (2021): 584-590.

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