Cholesteryl oleate-appended phthalocyanines as potential photosensitizers in the treatment of leishmaniasis
Sanchez Contreras LE, Zirzlmeier J, Kirner S, Setaro F, Martinez F, Lozada S, Escobar P, Hahn U, Guldi DM, Torres T (2015)
Publication Type: Journal article
Publication year: 2015
Journal
Book Volume: 19
Pages Range: 320-328
Journal Issue: 1-3
DOI: 10.1142/S1088424615500157
Abstract
Two phthalocyanines (Pcs) with either a zinc or a ruthenium metal at the center of the macrocycle have been functionalized by a cholesteryl oleate moiety. The potential photosensitizers (PSs) for the treatment of cutaneous leishmaniasis have been studied on their photophysical properties and their ability to generate singlet oxygen. These experiments corroborate that solvent mixtures containing variable ratios of THF and water impact the excited state deactivation. The compounds were used preloaded into LDL particles and their phototoxic activity was evaluated in a preliminary way.
Authors with CRIS profile
Johannes Zirzlmeier
Lehrstuhl für Physikalische Chemie I
Sabrina Kirner
Lehrstuhl für Physikalische Chemie I
Dirk Michael Guldi
Lehrstuhl für Physikalische Chemie I
Involved external institutions
Universidad Autónoma de Madrid (UAM)
Spain (ES)
Industrial University of Santander / Universidad Industrial de Santander
Colombia (CO)
Spain (ES)
Industrial University of Santander / Universidad Industrial de Santander
Colombia (CO)
How to cite
APA:
Sanchez Contreras, L.E., Zirzlmeier, J., Kirner, S., Setaro, F., Martinez, F., Lozada, S.,... Torres, T. (2015). Cholesteryl oleate-appended phthalocyanines as potential photosensitizers in the treatment of leishmaniasis. Journal of Porphyrins and Phthalocyanines, 19(1-3), 320-328. https://doi.org/10.1142/S1088424615500157
MLA:
Sanchez Contreras, Laura E., et al. "Cholesteryl oleate-appended phthalocyanines as potential photosensitizers in the treatment of leishmaniasis." Journal of Porphyrins and Phthalocyanines 19.1-3 (2015): 320-328.
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