Functional Specialization of Dendritic Cell Subsets

Heidkamp GF, Lehmann C, Heger L, Baransk A, Hoffmann A, Lühr J, Dudziak D (2016)

Publication Type: Book chapter / Article in edited volumes

Publication year: 2016

Publisher: Elsevier Inc.

Edited Volumes: Functional Cell Biology

Series: Encyclopedia of Cell Biology

Book Volume: 3

ISBN: 9780123944474

DOI: 10.1016/B978-0-12-394447-4.30076-1

Abstract

Dendritic cells (DCs) are sentinels of the immune system. Under inflammatory conditions DCs undergo various phenotypical changes, including DC migration, upregulation of co-stimulatory and activating molecules, secretion of cytokines, but also the processing of the engulfed antigens. The DC presents short antigenic peptides on the DC surface as peptide MHC class I or MHC class II complexes to CD8⁺ or CD4⁺ T cells, respectively. This article will provide a detailed overview on the antigen processing machineries and specialized functions of the increasing variety of DC subsets in mice and men.

Authors with CRIS profile

Gordon Frederik Heidkamp Department of Dermatology Christian Lehmann Department of Dermatology Lukas Heger Department of Dermatology Jennifer Lühr Department of Dermatology Diana Dudziak Professur für die Biologie Dendritischer Zellen

How to cite

APA:

Heidkamp, G.F., Lehmann, C., Heger, L., Baransk, A., Hoffmann, A., Lühr, J., & Dudziak, D. (2016). Functional Specialization of Dendritic Cell Subsets. In Ralph A. Bradshaw, Philip D. Stahl (Eds.), Functional Cell Biology. Elsevier Inc..

MLA:

Heidkamp, Gordon Frederik, et al. "Functional Specialization of Dendritic Cell Subsets." Functional Cell Biology. Ed. Ralph A. Bradshaw, Philip D. Stahl, Elsevier Inc., 2016.

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