Crystal arthropathies and osteoarthritis-where is the link?

Jarraya M, Roemer F, Kwoh CK, Guermazi A (2022)


Publication Type: Journal article, Review article

Publication year: 2022

Journal

DOI: 10.1007/s00256-022-04246-8

Abstract

Osteoarthritis (OA) is one of the leading causes of disability worldwide. As our understanding of OA progressively has moved from a purely mechanical "wear and tear " concept toward a complex multi-tissue condition in which inflammation plays a central role, the possible role of crystal-induced inflammation in OA incidence and progression may be relevant. In addition to gout, which affects 4% of the US population, basic calcium phosphate and calcium pyrophosphate deposition both may induce joint inflammation and may play a role in pain in OA. This narrative review article discusses the possible mechanisms underlying the associations between crystal-induced arthropathies and OA, and the important implications of these for clinical practice and future research.

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How to cite

APA:

Jarraya, M., Roemer, F., Kwoh, C.K., & Guermazi, A. (2022). Crystal arthropathies and osteoarthritis-where is the link? Skeletal Radiology. https://doi.org/10.1007/s00256-022-04246-8

MLA:

Jarraya, Mohamed, et al. "Crystal arthropathies and osteoarthritis-where is the link?" Skeletal Radiology (2022).

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