Effects of Renal Denervation vs Sham in Resistant Hypertension After Medication Escalation Prespecified Analysis at 6 Months of the RADIANCE-HTN TRIO Randomized Clinical Trial

Azizi M, Mahfoud F, Weber MA, Sharp ASP, Schmieder R, Lurz P, Lobo MD, Fisher NDL, Daemen J, Bloch MJ, Basile J, Sanghvi K, Saxena M, Gosse P, Jenkins JS, Levy T, Persu A, Kably B, Claude L, Reeve-Stoffer H, Mcclure C, Kirtane AJ (2022)

Publication Type: Journal article

Publication year: 2022

Journal

DOI: 10.1001/jamacardio.2022.3904

Abstract

IMPORTANCE Although early trials of endovascular renal denervation (RDN) for patients with resistant hypertension (RHTN) reported inconsistent results, ultrasound RDN (uRDN) was found to decrease blood pressure (BP) vs sham at 2 months in patients with RHTN taking stable background medications in the Study of the ReCor Medical Paradise System in Clinical Hypertension (RADIANCE-HTN TRIO) trial.

Authors with CRIS profile

Involved external institutions

Georges Pompidou European Hospital / Hôpital Européen Georges-Pompidou (HEGP) France (FR) Universitätsklinikum des Saarlandes (UKS) Germany (DE) State University of New York at Albany (UNY Albany / UAlbany) United States (USA) (US) Universität Leipzig Germany (DE) Queen Mary, University of London United Kingdom (GB) Brigham and Women's Hospital (BWH) United States (USA) (US) Erasmus University Medical Center (MC) Netherlands (NL) University of Nevada, Reno United States (USA) (US) Medical University of South Carolina (MUSC) United States (USA) (US) Deborah Heart and Lung Center United States (USA) (US) Centre Hospitalier Universitaire de Bordeaux / CHU Bordeaux France (FR) Ochsner Health System United States (USA) (US) Royal Bournemouth Hospital United Kingdom (GB) Université Catholique de Louvain (UCL) Belgium (BE) ReCor Medical Inc. United States (USA) (US) North American Science Associates (NAMSA) United States (USA) (US)

How to cite

APA:

Azizi, M., Mahfoud, F., Weber, M.A., Sharp, A.S.P., Schmieder, R., Lurz, P.,... Kirtane, A.J. (2022). Effects of Renal Denervation vs Sham in Resistant Hypertension After Medication Escalation Prespecified Analysis at 6 Months of the RADIANCE-HTN TRIO Randomized Clinical Trial. JAMA Cardiology. https://dx.doi.org/10.1001/jamacardio.2022.3904

MLA:

Azizi, Michel, et al. "Effects of Renal Denervation vs Sham in Resistant Hypertension After Medication Escalation Prespecified Analysis at 6 Months of the RADIANCE-HTN TRIO Randomized Clinical Trial." JAMA Cardiology (2022).

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