Resting-state networks as simultaneously measured with functional MRI and PET

Savio A, Fuenger S, Tahmasian M, Rachakonda S, Manoliu A, Sorg C, Grimmer T, Calhoun V, Drzezga A, Riedl V, Yakushev I (2017)

Publication Type: Journal article

Publication year: 2017

Journal

Journal of Nuclear Medicine Society of Nuclear Medicine

Book Volume: 58

Pages Range: 1314-1317

Journal Issue: 8

DOI: 10.2967/jnumed.116.185835

Abstract

Functional MRI (fMRI) stuDies reported Disruption of resting-state networks (RSNs) in several neuropsychiatric Disorders. PET with 18F-FDG captures neuronal activity that is in steady state at a longer time span and is less dependent on neurovascular coupling. Methods: In the present study, we aimed to identify RSNs in 18F-FDG PET data and compare their spatial pattern with those obtained from simultaneously acquired resting-state fMRI data in 22 middle-aged healthy subjects. Results: Thirteen and 17 meaningful RSNs could be identified in PET and fMRI data, respectively. Spatial overlap was fair tomoderate for the defaultmode, left central executive, primary and secondary visual, sensorimotor, cerebellar, and auDitory networks. Despite recorDing Different aspects of neural activity, similar RSNs were detected by both imaging modalities. Conclusion: The results argue for the common neural substrate of RSNs and encourage testing of the clinical utility of resting-state connectivity in PET data.

Authors with CRIS profile

Valentin Riedl

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) The Mind Research Network (MRN) US United States (USA) (US)

How to cite

APA:

Savio, A., Fuenger, S., Tahmasian, M., Rachakonda, S., Manoliu, A., Sorg, C.,... Yakushev, I. (2017). Resting-state networks as simultaneously measured with functional MRI and PET. Journal of Nuclear Medicine, 58(8), 1314-1317. https://doi.org/10.2967/jnumed.116.185835

MLA:

Savio, Alexandre, et al. "Resting-state networks as simultaneously measured with functional MRI and PET." Journal of Nuclear Medicine 58.8 (2017): 1314-1317.

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