Vaccination in older adults: Compulsory or voluntary exercise? Impfen im Alter - Pflicht oder Kür?
Kwetkat A, Endres AS, Leischker A, Heppner HJ (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 145
Pages Range: 1133-1137
Journal Issue: 16
DOI: 10.1055/a-1073-3171
Abstract
Background Immunosenescence leads to an increasing susceptibility to infections. Therefore, vaccination is an essential element of prevention. The recommendations of the permanent vaccination commission (STIKO), a committee at the Robert-Koch-Institute, affiliated to the German Government, are updated every year and include a particular section dealing with older adults. Current developments Immunosenescence reduces vaccine effectiveness. Thus, older adults and patients with multimorbidity are in need of more immunogenic vaccines. Cell culture derived quadrivalent influenza vaccine, trivalent adjuvanted vaccine and a high dose influenza vaccine show higher immune response in these groups. STIKO actually recommends an adjuvanted herpes zoster subunit vaccine to all adults in the age of 60 and above because of its vaccine effectiveness of 90 % in all age groups. The increasing travel activities of older adults require travel vaccination advice that takes into account travel destination as well as multimorbidity. Adjusted vaccination schedules and controlling of antibody titers have to be considered. Outlook New vaccines are under development, that are more immunogenic and therefore more effective (e. g. pneumococcal vaccine) or that prevent infections for which a vaccine was previously not available (e. g. norovirus vaccine).
Authors with CRIS profile
Involved external institutions
Evangelisches Geriatriezentrum Berlin (EGZB)
Germany (DE)
Alexianer Krefeld GmbH
Germany (DE)
Universitätsklinikum Jena
Germany (DE)
HELIOS Kliniken
Germany (DE)
Germany (DE)
Alexianer Krefeld GmbH
Germany (DE)
Universitätsklinikum Jena
Germany (DE)
HELIOS Kliniken
Germany (DE)
How to cite
APA:
Kwetkat, A., Endres, A.-S., Leischker, A., & Heppner, H.J. (2020). Vaccination in older adults: Compulsory or voluntary exercise? Impfen im Alter - Pflicht oder Kür? Deutsche Medizinische Wochenschrift, 145(16), 1133-1137. https://dx.doi.org/10.1055/a-1073-3171
MLA:
Kwetkat, Anja, et al. "Vaccination in older adults: Compulsory or voluntary exercise? Impfen im Alter - Pflicht oder Kür?" Deutsche Medizinische Wochenschrift 145.16 (2020): 1133-1137.
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