Odorant Metabolism in Humans

Kornbausch N, Debong M, Büttner A, Heydel JM, Loos H (2022)

Publication Type: Journal article, Review article

Publication year: 2022

Journal

Angewandte Chemie International Edition Wiley

Book Volume: 61

Journal Issue: 35

DOI: 10.1002/anie.202202866

Abstract

Odorants are relatively small molecules which are easily taken up and distributed in the human body. Despite their relevance in everyday life, however, only a limited amount of evidence about their metabolism, pathways, and bioactivities in the human body exists. With this Review, we aim to encourage future interdisciplinary research on the function and mechanisms of the biotransformation of odorants, involving different disciplines such as nutrition, medicine, biochemistry, chemistry, and sensory sciences. Starting with a general overview of the different ways of odorant uptake and enzymes involved in the metabolism of odorants, a more precise description of biotransformation processes and their function in the oral cavity, the nose, the lower respiratory tract (LRT), and the gastrointestinal tract (GIT) is given together with an overview of the different routes of odorant excretion. Finally, perspectives for future research are discussed.

Authors with CRIS profile

Nicole Kornbausch Lehrstuhl für Aroma- und Geruchsforschung Marcel Debong Lehrstuhl für Aroma- und Geruchsforschung Andrea Büttner Lehrstuhl für Aroma- und Geruchsforschung Helene Loos Lehrstuhl für Aroma- und Geruchsforschung

Additional Organisation(s)

Emil-Fischer-Zentrum (Emil Fischer Center)

Involved external institutions

Université Bourgogne Franche-Comté FR France (FR)

How to cite

APA:

Kornbausch, N., Debong, M., Büttner, A., Heydel, J.-M., & Loos, H. (2022). Odorant Metabolism in Humans. Angewandte Chemie International Edition, 61(35). https://doi.org/10.1002/anie.202202866

MLA:

Kornbausch, Nicole, et al. "Odorant Metabolism in Humans." Angewandte Chemie International Edition 61.35 (2022).

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