Characterizing the degradation behavior of bioceramic scaffolds

Goudouri OM, Balasubramanian P, Boccaccini AR (2016)

Publication Type: Authored book

Publication year: 2016

Publisher: Elsevier Inc.

ISBN: 9781782420958

DOI: 10.1016/B978-1-78242-087-3.00006-7


The use of bioceramic scaffolds for hard tissue repair, augmentation, and substitution is continuously increasing in many dental and medical applications. It is well established that the in vivo biodegradation and bioresorption of ceramic scaffolds at rates appropriate to tissue regeneration play a vital role in enabling new tissue formation. Furthermore, the various ionic by-products of biodegradation of scaffolding materials result in the enrichment of the microenvironment, which can affect, positively or negatively, the proliferation and activity of cells. Therefore, the factors affecting degradation or the extent of dissolution of the scaffolding materials are important. The aim of this chapter is to discuss the processes of biodegradation or bioresorption of bioceramic scaffolds in terms of the physical, chemical, and biocompatibility that occur when in contact with simulated body fluids, cells, or living tissue, focusing on the applied characterization techniques.

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Goudouri, O.M., Balasubramanian, P., & Boccaccini, A.R. (2016). Characterizing the degradation behavior of bioceramic scaffolds. Elsevier Inc..


Goudouri, Ourania Menti, Preethi Balasubramanian, and Aldo R. Boccaccini. Characterizing the degradation behavior of bioceramic scaffolds. Elsevier Inc., 2016.

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