Multifunctional scaffolds for bone tissue engineering and in situ drug delivery

Mouriño V, Cattalini JP, Li W, Boccaccini AR, Lucangioli S (2014)

Publication Type: Authored book

Publication year: 2014

Publisher: Elsevier Inc.

ISBN: 9780857097163

Abstract

This chapter provides an overview about the development of bone tissue engineering scaffolds with the ability to provide the controlled delivery of therapeutic drugs. Typical drugs considered include gentamicin and other antibiotics generally used to combat osteomyelitis as well as anti-inflammatory drugs and bisphosphonates. Special attention has been given to the technology used for controlling the release of the loaded drugs. A detailed summary of drugs included in bone tissue scaffolds is presented and the many approaches developed to combine organic and inorganic biomaterials in composites for drug-delivery systems are discussed. The remaining challenges in the field are summarized, suggesting also future research directions.

Authors with CRIS profile

Wenjie Li Lehrstuhl für Glas und Keramik Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Universidad de Buenos Aires (UBA) / University of Buenos Aires

Argentina (AR)

How to cite

APA:

Mouriño, V., Cattalini, J.P., Li, W., Boccaccini, A.R., & Lucangioli, S. (2014). Multifunctional scaffolds for bone tissue engineering and in situ drug delivery. Elsevier Inc..

MLA:

Mouriño, V., et al. Multifunctional scaffolds for bone tissue engineering and in situ drug delivery. Elsevier Inc., 2014.

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