Pancreatic neuroendocrine neoplasms - Update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours)

Kos-Kudła B, Rosiek V, Borowska M, Bednarczuk T, Bolanowski M, Chmielik E, Ćwikla JB, Foltyn W, Gisterek I, Handkiewicz-Junak D, Hubalewska-Dydejczyk A, Jarząb M, Junik R, Kajdaniuk D, Kamiński G, Kolasińska-Ćwikla A, Kowalska A, Królicki L, Kunikowska J, Kuśnierz K, Lewiński A, Liszka Ł, Londzin-Olesik M, Marek B, Malczewska A, Nasierowska-Guttmejer A, Nowakowska-Dulawa E, Pavel ME, Pilch-Kowalczyk J, Reguła J, Ruchała M, Rydzewska G, Siemińska L, Sowa-Staszczak A, Starzyńska T, Stojčev Z, Strzelczyk J, Studniarek M, Syrenicz A, Szczepkowski M, Wachula E, Zajȩcki W, Zemczak A, Zgliczyński W, Zieniewicz K (2022)


Publication Type: Journal article

Publication year: 2022

Journal

Book Volume: 73

Pages Range: 491-548

Journal Issue: 3

DOI: 10.5603/EP.a2022.0050

Abstract

In this paper, we present the current guidelines for the diagnostics and management of pancreatic neuroendocrine neoplasms (PanNENs) developed by Polish experts providing care for these patients in everyday clinical practice. In oncological diagnostics, in addition to biochemical tests, molecular identification with the use of NETest liquid biopsy and circulating microRNAs is gaining importance. Both anatomical and functional examinations (including new radiopharmaceuticals) are used in imaging diagnostics. Histopathological diagnosis along with immunohistochemical examination still constitute the basis for therapeutic decisions. Whenever possible, surgical procedure is the treatment of choice. Pharmacological management including biotherapy, radioisotope therapy, targeted molecular therapy, and chemotherapy are important methods of systemic therapy. Treatment of PanNENs requires a multidisciplinary team of specialists in the field of neuroendocrine neoplasms.

Authors with CRIS profile

Involved external institutions

How to cite

APA:

Kos-Kudła, B., Rosiek, V., Borowska, M., Bednarczuk, T., Bolanowski, M., Chmielik, E.,... Zieniewicz, K. (2022). Pancreatic neuroendocrine neoplasms - Update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours). Endokrynologia Polska, 73(3), 491-548. https://doi.org/10.5603/EP.a2022.0050

MLA:

Kos-Kudła, Beata, et al. "Pancreatic neuroendocrine neoplasms - Update of the diagnostic and therapeutic guidelines (recommended by the Polish Network of Neuroendocrine Tumours)." Endokrynologia Polska 73.3 (2022): 491-548.

BibTeX: Download