HINGEneering IgG for enhanced immune activation

Werner A, Nimmerjahn F (2022)

Publication Type: Journal article, Review article

Publication year: 2022

Journal

Science immunology American Association for the Advancement of Science

Book Volume: 7

Pages Range: eabq4797-

Journal Issue: 73

DOI: 10.1126/sciimmunol.abq4797

Abstract

Two recent studies in Science Immunology by Orr et al. and Foss et al. demonstrate that the hinge region of immunoglobulin G (IgG) is a major regulator of IgG2 and IgG3 activity, respectively. Engineering of the IgG hinge may therefore be useful for optimizing the activity of IgG subclasses.

Authors with CRIS profile

Anja Werner Lehrstuhl für Genetik Falk Nimmerjahn Lehrstuhl für Genetik

How to cite

APA:

Werner, A., & Nimmerjahn, F. (2022). HINGEneering IgG for enhanced immune activation. Science immunology, 7(73), eabq4797-. https://doi.org/10.1126/sciimmunol.abq4797

MLA:

Werner, Anja, and Falk Nimmerjahn. "HINGEneering IgG for enhanced immune activation." Science immunology 7.73 (2022): eabq4797-.

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