Bis(4-carboxylpyrazol-1-yl)acetic acid: a scorpionate ligand for complexes with improved water solubility

Tzegai W, Reil M, Burzlaff N (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Dalton Transactions Royal Society of Chemistry

DOI: 10.1039/d2dt00848c

Abstract

Bis(4-carboxylpyrazol-1-yl)acetic acid (H(3)bcpza) (2), obtained in a one-pot synthesis, contains carboxyl groups that differ in their pK(a) values. The ligand exhibits heteroscorpionate kappa(3)-N,N,O-coordination whereupon the peripheral carboxyl groups are not involved in metal binding. The corresponding carbonyl complexes [Mn(H(2)bcpza)(CO)(3)] (4), [Re(H(2)bcpza)(CO)(3)] (5) and [Ru(H(2)bcpza)Cl(CO)(2)] (6a/6b) are partially soluble in water but readily soluble in PBS buffer.

Authors with CRIS profile

Wintana Tzegai Lehrstuhl für Anorganische und Metallorganische Chemie Michaela Reil Lehrstuhl für Anorganische und Metallorganische Chemie Nicolai Burzlaff Professur für Anorganische Chemie

How to cite

APA:

Tzegai, W., Reil, M., & Burzlaff, N. (2022). Bis(4-carboxylpyrazol-1-yl)acetic acid: a scorpionate ligand for complexes with improved water solubility. Dalton Transactions. https://dx.doi.org/10.1039/d2dt00848c

MLA:

Tzegai, Wintana, Michaela Reil, and Nicolai Burzlaff. "Bis(4-carboxylpyrazol-1-yl)acetic acid: a scorpionate ligand for complexes with improved water solubility." Dalton Transactions (2022).

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