Stress Pathways to Disease

Rohleder N, Rohleder N (2021)


Publication Type: Conference contribution

Publication year: 2021

Journal

Publisher: PERGAMON-ELSEVIER SCIENCE LTD

City/Town: OXFORD

Pages Range: S27-S27

Conference Proceedings Title: PSYCHONEUROENDOCRINOLOGY

DOI: 10.1016/j.psyneuen.2021.105544

Abstract

Psychosocial stress is an important precursor of disease and reduced quality of life in humans. The biological pathways between stress exposure and pathophysiological processes underlying disease have received substantial attention, primarily focusing on the role of the hypothalamus pituitary adrenal (HPA) axis and sympathetic nervous system (SNS). How activation of these stress systems translates into physiological disease, however, remain insufficiently understood. Recent research has therefore focused on systemic low-grade inflammation as a promising pathway, because (a) stress systems are known to affect the inflammatory system, (b) elevated inflammatory system activity often accompanies chronic psychosocial distress, and (c) inflammation plays a key role in the pathophysiology of diseases such as cardiovascular disease, type2 diabetes, and cancer. Data will be presented addressing different aspects of stress system control of inflammatory mechanisms in the context of chronic and acute psychosocial stress.

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How to cite

APA:

Rohleder, N., & Rohleder, N. (2021). Stress Pathways to Disease. In PSYCHONEUROENDOCRINOLOGY (pp. S27-S27). OXFORD: PERGAMON-ELSEVIER SCIENCE LTD.

MLA:

Rohleder, N., and Nicolas Rohleder. "Stress Pathways to Disease." Proceedings of the PSYCHONEUROENDOCRINOLOGY OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2021. S27-S27.

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