Gpr126 domains control different cellular mechanisms of ventricular chamber development

Srivastava S, Gunanwan F, Guenther S, Ferrazzi F, Gentile A, Monk KM, Stainier DYR, Engel F (2021)

Publication Type: Conference contribution

Publication year: 2021

Journal

European Heart Journal Oxford University Press

Publisher: OXFORD UNIV PRESS

City/Town: OXFORD

Pages Range: 3180-3180

Conference Proceedings Title: EUROPEAN HEART JOURNAL

DOI: 10.1093/eurheartj/ehab724.3180

Abstract

Trabeculation is a crucial process during ventricular chamber development which describes the protrusion of cardiomyocytes into the lumen of the ventricular chamber to form complex muscular structures called trabeculae. Defects in this process results in various human diseases such as left ventricular non compaction cardiomyopathies and other congenital heart defects. Several cellular mechanisms have been identified underlying trabeculation including tension heterogeneity induced cardiomyocyte selection, depolarization and delamination. However, the molecular mechanisms governing trabeculation are still poorly understood.

Authors with CRIS profile

Fulvia Ferrazzi Department of Nephropathology Felix Engel Department of Nephropathology

Involved external institutions

Max Planck Institute for Heart and Lung Research / Max-Planck-Institut für Herz- und Lungenforschung DE Germany (DE) Oregon Health and Science University (OSHU) US United States (USA) (US)

How to cite

APA:

Srivastava, S., Gunanwan, F., Guenther, S., Ferrazzi, F., Gentile, A., Monk, K.M.,... Engel, F. (2021). Gpr126 domains control different cellular mechanisms of ventricular chamber development. In EUROPEAN HEART JOURNAL (pp. 3180-3180). OXFORD: OXFORD UNIV PRESS.

MLA:

Srivastava, Swati, et al. "Gpr126 domains control different cellular mechanisms of ventricular chamber development." Proceedings of the EUROPEAN HEART JOURNAL OXFORD: OXFORD UNIV PRESS, 2021. 3180-3180.

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