Crypts in Asymmetric Fission in Endoscopic Biopsies from German Patients With Inflammatory Bowel Disease

Rubio CA, Lang-Schwarz C, Vieth M (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Anticancer Research International Institute of Anticancer Research (IIAR)

Book Volume: 41

Pages Range: 4401-4405

Journal Issue: 9

DOI: 10.21873/anticanres.15245

Abstract

Background/Aim: We previously found in Swedish patients with inflammatory bowel disease (IBD), crypts in symmetric fission (CSF) and in asymmetric fission (CAF). This study aimed to examine CSF and CAF in a cohort of German patients with IBD. Patients and Methods: H&E-sections from 106 IBD-patients [59 ulcerative colitis (UC) and 47 Crohn colitis (CCs)] were analysed. Results: A total of 588 crypts in fission (CF) were found; 342 (58.2%) in UC and 246 (41.8%) in CCs. Out of the 505 CAFs found, 304 (60.2%) were recorded in UC, and 201(39.8%) in CCs (p=0.15272). Conclusion: Despite that German and Swedish populations reside in disparate geographical regions with different ecological milieus, the proportions of CAF and CSF were similar, thereby suggesting that CAF and CSF develop in IBD independently of the local environmental conditions in the two regions.

Authors with CRIS profile

Corinna Lang-Schwarz Medizinische Fakultät Michael Vieth Professur für Allgemeine Pathologie

Involved external institutions

Karolinska Institute SE Sweden (SE)

How to cite

APA:

Rubio, C.A., Lang-Schwarz, C., & Vieth, M. (2021). Crypts in Asymmetric Fission in Endoscopic Biopsies from German Patients With Inflammatory Bowel Disease. Anticancer Research, 41(9), 4401-4405. https://doi.org/10.21873/anticanres.15245

MLA:

Rubio, Carlos A., Corinna Lang-Schwarz, and Michael Vieth. "Crypts in Asymmetric Fission in Endoscopic Biopsies from German Patients With Inflammatory Bowel Disease." Anticancer Research 41.9 (2021): 4401-4405.

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