Hair cortisol concentration in patients with active central serous chorioretinopathy is elevated – a pilot study
Lenk J, Sandner D, Schindler L, Pillunat LE, Matthe E (2019)
Publication Type: Journal article
Publication year: 2019
Journal
Book Volume: 97
Pages Range: e568-e571
Journal Issue: 4
DOI: 10.1111/aos.13979
Abstract
Purpose: To investigate hair cortisol concentration (HCC), a biochemical correlate of long-term cortisol output patterns, and its relationship to active central serous chorioretinopathy (CSC). Methods: Twenty-six participants were included in this observational pilot study (11 patients with active CSC and 15 healthy controls). Hair cortisol concentrations (HCCs) were determined from 3 cm hair strands collected near the scalp from patients and controls as an index of cumulative cortisol secretion over the 3-month period prior to hair sampling. Results: Patients with CSC exhibited higher HCCs (mean value: 20.14, 95% CI: 14.89–27.16 pg/mg) than healthy controls (mean value: 11.06, 95% CI: 8.63–14.22 pg/mg, p = 0.008). Group differences were not affected by relevant covariates (BMI, smoking status, sex). Conclusion: Patients with active CSC have increased HCC, supporting the fact that cortisol is a major player in CSC pathogenesis.
Authors with CRIS profile
Involved external institutions
Germany (DE)How to cite
APA:
Lenk, J., Sandner, D., Schindler, L., Pillunat, L.E., & Matthe, E. (2019). Hair cortisol concentration in patients with active central serous chorioretinopathy is elevated – a pilot study. Acta Ophthalmologica, 97(4), e568-e571. https://doi.org/10.1111/aos.13979
MLA:
Lenk, Janine, et al. "Hair cortisol concentration in patients with active central serous chorioretinopathy is elevated – a pilot study." Acta Ophthalmologica 97.4 (2019): e568-e571.
BibTeX: Download