Process design and optimization

Jupke A, Biselli A, Kaspereit M, Leipnitz M, Schmidt-Traub H (2020)

Publication Type: Book chapter / Article in edited volumes

Publication year: 2020

Publisher: John Wiley & Sons, Ltd.

Edited Volumes: Preparative Chromatography: Third Edition

Pages Range: 409-501

ISBN: 9783527816347

DOI: 10.1002/9783527816347.ch8


The design and optimization of chromatographic separation processes requires profound knowledge of effects taking place in a chromatographic column. Based on fundamental knowledge from previous chapters, in this chapter, the reader is directed through current design and optimization strategies for continuous and discontinuous chromatographic separation processes. Thereby, illustrative examples, mainly based on rigorous simulation models, support the reader's process understanding. After reading the present chapter, the reader will be able to apply design and optimization strategies to varying separation tasks.

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Jupke, A., Biselli, A., Kaspereit, M., Leipnitz, M., & Schmidt-Traub, H. (2020). Process design and optimization. In Henner Schmit-Traub, Michael Schulte, Andreas Seidel-Morgenstern (Eds.), Preparative Chromatography: Third Edition. (pp. 409-501). John Wiley & Sons, Ltd..


Jupke, Andreas, et al. "Process design and optimization." Preparative Chromatography: Third Edition. Ed. Henner Schmit-Traub, Michael Schulte, Andreas Seidel-Morgenstern, John Wiley & Sons, Ltd., 2020. 409-501.

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