Emerging Entities and New Diagnostic Markers for Head and Neck Soft Tissue and Bone Tumors

Franchi A, Thompson LD, Hernandez-Prera JC, Agaimy A, Williams MD, Mikkelsen LH, Bishop JA, Willems SM, Hellquist H, Ferlito A (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Advances in Anatomic Pathology Lippincott, Williams & Wilkins

Book Volume: 28

Pages Range: 139-149

Journal Issue: 3

DOI: 10.1097/PAP.0000000000000295

Abstract

Bone and soft tissue tumors of the head and neck are relatively uncommon tumors that often represent a diagnostic challenge because of the wide range of entities that must be considered in the differential diagnosis. Over the past few years, classification of bone and soft tissue tumors has evolved primarily because of substantial contributions from molecular genetics, with the identification of new markers that are increasingly used to complement histopathologic findings in the routine diagnostic workup. This review focuses on the recently described mesenchymal tumors that preferentially involve the head and neck region, with a focus on the most relevant novel immunohistochemical and molecular findings, including gene fusions and mutations, that can help in the diagnosis and in the assessment of clinical behavior.

Authors with CRIS profile

Abbas Agaimy Lehrstuhl für Allgemeine Pathologie und Pathologische Anatomie

Involved external institutions

International Head and Neck Scientific Group DE Germany (DE) University of Algarve / Universidade do Algarve PT Portugal (PT) University Medical Centre Utrecht (UMC Utrecht) NL Netherlands (NL) University of Texas Southwestern Medical Center (UT Southwestern) US United States (USA) (US) Rigshospitalet DK Denmark (DK) University of Texas MD Anderson Cancer Center US United States (USA) (US) H. Lee Moffitt Cancer Center & Research Institute US United States (USA) (US) Kaiser Permanente US United States (USA) (US) University of Pisa / Università di Pisa (UniPi) IT Italy (IT)

How to cite

APA:

Franchi, A., Thompson, L.D., Hernandez-Prera, J.C., Agaimy, A., Williams, M.D., Mikkelsen, L.H.,... Ferlito, A. (2021). Emerging Entities and New Diagnostic Markers for Head and Neck Soft Tissue and Bone Tumors. Advances in Anatomic Pathology, 28(3), 139-149. https://doi.org/10.1097/PAP.0000000000000295

MLA:

Franchi, Alessandro, et al. "Emerging Entities and New Diagnostic Markers for Head and Neck Soft Tissue and Bone Tumors." Advances in Anatomic Pathology 28.3 (2021): 139-149.

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