The special developmental biology of craniofacial tissues enables the understanding of oral and maxillofacial physiology and diseases

Weber M, Wehrhan F, Deschner J, Sander J, Ries J, Möst T, Bozec A, Gölz L, Kesting MR, Lutz R (2021)

Publication Type: Journal article, Review article

Publication year: 2021

Journal

International Journal of Molecular Sciences MDPI

Book Volume: 22

Pages Range: 1-15

Article Number: 1315

Journal Issue: 3

DOI: 10.3390/ijms22031315

Abstract

Maxillofacial hard tissues have several differences compared to bones of other localiza-tions of the human body. These could be due to the different embryological development of the jaw bones compared to the extracranial skeleton. In particular, the immigration of neuroectodermally differentiated cells of the cranial neural crest (CNC) plays an important role. These cells differ from the mesenchymal structures of the extracranial skeleton. In the ontogenesis of the jaw bones, the development via the intermediate stage of the pharyngeal arches is another special developmental feature. The aim of this review was to illustrate how the development of maxillofacial hard tissues occurs via the cranial neural crest and pharyngeal arches, and what significance this could have for relevant pathologies in maxillofacial surgery, dentistry and orthodontic therapy. The pathogenesis of various growth anomalies and certain syndromes will also be discussed.

Authors with CRIS profile

Manuel Weber Department of Oral and Cranio-Maxillofacial Surgery Falk Wehrhan Department of Oral and Cranio-Maxillofacial Surgery Janina Sander Department of Oral and Cranio-Maxillofacial Surgery Jutta Ries Medizinische Fakultät Tobias Möst Department of Oral and Cranio-Maxillofacial Surgery Aline Bozec Juniorprofessur für Osteoimmunologie Lina Gölz Lehrstuhl für Zahn-, Mund- und Kieferheilkunde, insbesondere Kieferorthopädie Marco Rainer Kesting Lehrstuhl für Zahnmedizin, insbesondere Mund-, Kiefer-, und Gesichtschirurgie Rainer Lutz Department of Oral and Cranio-Maxillofacial Surgery

Involved external institutions

Johannes Gutenberg-Universität Mainz (JGU) DE Germany (DE)

How to cite

APA:

Weber, M., Wehrhan, F., Deschner, J., Sander, J., Ries, J., Möst, T.,... Lutz, R. (2021). The special developmental biology of craniofacial tissues enables the understanding of oral and maxillofacial physiology and diseases. International Journal of Molecular Sciences, 22(3), 1-15. https://doi.org/10.3390/ijms22031315

MLA:

Weber, Manuel, et al. "The special developmental biology of craniofacial tissues enables the understanding of oral and maxillofacial physiology and diseases." International Journal of Molecular Sciences 22.3 (2021): 1-15.

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