COVID-19 und Schwangerschaft: Fallserie mit der Komorbidität Diabetes aus der Registerstudie „Covid-19 Related Obstetric and Neonatal Outcome Study“ (CRONOS)

Kleinwechter H, Groten T, Schäfer-Graf U, Bohlmann MK, Ehrhardt I, Hein A, Hepp V, Hollatz-Galluschki E, Kraft K, Kunze M, Lihs A, Méndez-Martorell E, Oppelt P, Ramsauer B, Ravnaq-Möllers T, Riebe B, Rohlwink C, Rübelmann T, Pecks U (2020)

Publication Type: Journal article

Publication year: 2020

Journal

DOI: 10.1007/s11428-020-00701-z

Abstract

From March 3 to October 13, 2020, 27 cases with diabetes comorbidity have been recorded in the CRONOS registry (Covid-19 Related Obstetric and Neonatal Outcome Study in Germany) among 262 registered women with SARS-CoV‑2 infection during their pregnancy. Of those, 21 presented with gestational diabetes, 5 with type 2 diabetes and 1 with type 1 diabetes. About half of the women were asymptomatic and were diagnosed via general screening at hospital admission. The most common symptoms were nasal congestion, cough, tiredness, malaise and changes in smell and taste. The majority of pregnant women showed a mild to moderate course, three women were admitted to the intensive care unit and none required invasive ventilation. In the type 2 diabetes group, there were two cases with late fetal death (37 and 40 weeks of gestation) and one with a malformation, an association with diabetes being most likely. Pregnant women with diabetes mellitus represent a special subgroup; 1 in 10 women in this small cohort required intensive care monitoring due to COVID-19. In addition, this case series underscores the need for unrestricted access to pregnancy care, especially in times of pandemic, for optimal perinatal outcome.

Authors with CRIS profile

Involved external institutions

Universitätsklinikum Schleswig-Holstein (UKSH) Germany (DE) Vivantes - Netzwerk für Gesundheit GmbH Germany (DE) Universitätsklinikum Jena Germany (DE) Krankenhaus Landshut-Achdorf (LAKUMED) Germany (DE) Klinikum Weiden Germany (DE) Klinikum Links der Weser Germany (DE) Klinikum Dortmund Germany (DE) Kepler Universitätsklinikum (KUK) Austria (AT) St. Elisabethen Krankenhaus Germany (DE) Asklepios Kliniken Germany (DE) Klinikum Dritter Orden Germany (DE) Universitätsklinikum Freiburg Germany (DE) München Klinik gGmbH Germany (DE) Klinikum Starnberg Germany (DE) Klinikum Stuttgart Germany (DE) Klinik Hallerwiese Germany (DE)

How to cite

APA:

Kleinwechter, H., Groten, T., Schäfer-Graf, U., Bohlmann, M.K., Ehrhardt, I., Hein, A.,... Pecks, U. (2020). COVID-19 und Schwangerschaft: Fallserie mit der Komorbidität Diabetes aus der Registerstudie „Covid-19 Related Obstetric and Neonatal Outcome Study“ (CRONOS). Diabetologe. https://doi.org/10.1007/s11428-020-00701-z

MLA:

Kleinwechter, Helmut, et al. "COVID-19 und Schwangerschaft: Fallserie mit der Komorbidität Diabetes aus der Registerstudie „Covid-19 Related Obstetric and Neonatal Outcome Study“ (CRONOS)." Diabetologe (2020).

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