Recent Advances and Prospects in the Research of Nascent Adhesions

Stumpf H, Ambriović-Ristov A, Radenovic A, Smith AS (2020)

Publication Type: Journal article, Review article

Publication year: 2020

Journal

Frontiers in Physiology Frontiers Media

Book Volume: 11

Article Number: 574371

DOI: 10.3389/fphys.2020.574371

Abstract

Nascent adhesions are submicron transient structures promoting the early adhesion of cells to the extracellular matrix. Nascent adhesions typically consist of several tens of integrins, and serve as platforms for the recruitment and activation of proteins to build mature focal adhesions. They are also associated with early stage signaling and the mechanoresponse. Despite their crucial role in sampling the local extracellular matrix, very little is known about the mechanism of their formation. Consequently, there is a strong scientific activity focused on elucidating the physical and biochemical foundation of their development and function. Precisely the results of this effort will be summarized in this article.

Authors with CRIS profile

Henning Stumpf Physics Underlying Life Science (PULS) Ana-Suncana Smith Physics Underlying Life Science (PULS)

Involved external institutions

Rudjer Boskovic Institute (RBI) / Institut Ruđer Bošković (IRB)

Croatia (HR) École Polytechnique Fédérale de Lausanne (EPFL)

Switzerland (CH)

How to cite

APA:

Stumpf, H., Ambriović-Ristov, A., Radenovic, A., & Smith, A.-S. (2020). Recent Advances and Prospects in the Research of Nascent Adhesions. Frontiers in Physiology, 11. https://doi.org/10.3389/fphys.2020.574371

MLA:

Stumpf, Henning, et al. "Recent Advances and Prospects in the Research of Nascent Adhesions." Frontiers in Physiology 11 (2020).

BibTeX: Download