Smartphone-based multimodal tethered capsule endoscopic platform for white-light, narrow-band, and fluorescence/autofluorescence imaging
Sharma G, Thoma OM, Blessing K, Gal R, Waldner M, Singh K (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Abstract
Multimodal low-cost endoscopy is highly desirable in poor resource settings such as in developing nations. In this work, we developed a smartphone-based low-cost, reusable tethered capsule endoscopic platform that allows white-light, narrowband, and fluorescence/autofluorescence imaging of the esophagus. The ex-vivo studies of swine esophagus were performed and compared with a commercial endoscope to test the white-light imaging capabilities of the endoscope. The efficacy of the capsule for narrow-band imaging was tested by imaging the vascularization of the tongue. To determine the autofluorescence/fluorescence capability of the endoscope, fluorescein dye with different concentrations was imaged. Furthermore, swine esophagus injected with fluorescein dye was imaged using the fluorescence/autofluorescence and the white-light imaging modules, ex-vivo. The overall cost of the capsules is approximately 12 euro, 15 euro, and 42 euro for the white light imaging, the narrow-band imaging, and the fluorescence/autofluorescence imaging respectively. In addition, the cost of the laser source module required for the narrow-band imaging and the fluorescence/autofluorescence imaging is approximately 218 euro. This device will open the possibility of imaging the esophagus in underprivileged areas.
Authors with CRIS profile
Oana-Maria Thoma
Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology
Maximilian Waldner
Professur für Funktionelle Bildgebung in der Medizin
Additional Organisation(s)
Involved external institutions
Germany (DE)How to cite
APA:
Sharma, G., Thoma, O.-M., Blessing, K., Gal, R., Waldner, M., & Singh, K. (2020). Smartphone-based multimodal tethered capsule endoscopic platform for white-light, narrow-band, and fluorescence/autofluorescence imaging. Journal of Biophotonics. https://doi.org/10.1002/jbio.202000324
MLA:
Sharma, Gargi, et al. "Smartphone-based multimodal tethered capsule endoscopic platform for white-light, narrow-band, and fluorescence/autofluorescence imaging." Journal of Biophotonics (2020).
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