Enhancing orthopedic implant bioactivity: Refining the nanotopography

Wang G, Moya S, Lu Z, Gregurec D, Zreiqat H (2015)

Publication Type: Journal article, Review article

Publication year: 2015

Journal

Nanomedicine Future Medicine

Book Volume: 10

Pages Range: 1327-1341

Journal Issue: 8

DOI: 10.2217/nnm.14.216

Abstract

Advances in nanotechnology open up new possibilities to produce biomimetic surfaces that resemble the cell in vivo growth environment at a nanoscale level. Nanotopographical changes of biomaterials surfaces can positively impact the bioactivity and ossointegration properties of orthopedic and dental implants. This review introduces nanofabrication techniques currently used or those with high potential for use as surface modification of biomedical implants. The interactions of nanotopography with water, proteins and cells are also discussed, as they largely determine the final success of the implants. Due to the well-documented effects of surface chemistry and microtopography on the bioactivity of the implant, we here elaborate on the ability of the nanofabrication techniques to combine the dual (multi) modification of surface chemistry and/or microtopography.

Authors with CRIS profile

Danijela Gregurec

Involved external institutions

CIC biomaGUNE (Centro de Investigación Cooperativa en Biomateriales) ES Spain (ES) University of Sydney (USYD) AU Australia (AU)

How to cite

APA:

Wang, G., Moya, S., Lu, Z., Gregurec, D., & Zreiqat, H. (2015). Enhancing orthopedic implant bioactivity: Refining the nanotopography. Nanomedicine, 10(8), 1327-1341. https://doi.org/10.2217/nnm.14.216

MLA:

Wang, Guocheng, et al. "Enhancing orthopedic implant bioactivity: Refining the nanotopography." Nanomedicine 10.8 (2015): 1327-1341.

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