Empfehlung zum differenzierten Einsatz nuklearmedizinischer Diagnostik bei Parkinson-Syndromen
van Eimeren T, Claßen J, Drzezga A, Eggers C, Hilker-Roggendorf R, Klucken J, Koschel J, Meyer PT, Redecker C, Theis H, Buhmann C (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 88
Pages Range: 609-619
Journal Issue: 9
DOI: 10.1055/a-1207-0515
Abstract
The present work provides an overview of the various nuclear medicine methods in the diagnosis of neurodegenerative parkinsonian syndromes and their respective evidence and is intended to enable practical decision-making aids in the application and interpretation of the methods and findings. The value of the procedures differs considerably in relation to the two relevant diagnostic questions. On the one hand, it is the question of whether there is a neurodegenerative parkinsonian syndrome at all, and on the other hand the question of which one. While the DAT-SPECT is undisputedly the method of choice for answering the first question (taking certain parameters into account), this method is not suitable for answering the second question. To categorise parkinsonian syndromes into idiopathic (i. e. Parkinson´s disease) or atypical, various procedures are used in everyday clinical practice including MIBG scintigraphy, and FDG-PET. We explain why FDG-PET currently is not only the most suitable of these methods to differentiate an idiopathic parkinsonian syndrome, from an atypical Parkinson's syndrome, but also enables sufficiently valid to distinguish the various atypical neurodegenerative Parkinson's syndromes (i. e. MSA, PSP and CBD) from each other and therefore should be reimbursed by health insurances.
Authors with CRIS profile
Involved external institutions
Universitätsklinikum Freiburg
Germany (DE)
Universitätsklinikum Leipzig
Germany (DE)
Klinikum Lippe
Germany (DE)
Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)
Germany (DE)
Universitätsklinikum Gießen und Marburg (UKGM)
Germany (DE)
Universitätsklinikum Hamburg-Eppendorf (UKE)
Germany (DE)
Parkinson-Klinik Ortenau
Germany (DE)
Universitätsklinikum Köln
Germany (DE)
Germany (DE)
Universitätsklinikum Leipzig
Germany (DE)
Klinikum Lippe
Germany (DE)
Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)
Germany (DE)
Universitätsklinikum Gießen und Marburg (UKGM)
Germany (DE)
Universitätsklinikum Hamburg-Eppendorf (UKE)
Germany (DE)
Parkinson-Klinik Ortenau
Germany (DE)
Universitätsklinikum Köln
Germany (DE)
How to cite
APA:
van Eimeren, T., Claßen, J., Drzezga, A., Eggers, C., Hilker-Roggendorf, R., Klucken, J.,... Buhmann, C. (2020). Empfehlung zum differenzierten Einsatz nuklearmedizinischer Diagnostik bei Parkinson-Syndromen. Fortschritte der Neurologie - Psychiatrie, 88(9), 609-619. https://doi.org/10.1055/a-1207-0515
MLA:
van Eimeren, Thilo, et al. "Empfehlung zum differenzierten Einsatz nuklearmedizinischer Diagnostik bei Parkinson-Syndromen." Fortschritte der Neurologie - Psychiatrie 88.9 (2020): 609-619.
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