Becker R, Leone M, Engel F (2020)
Publication Type: Journal article, Review article
Publication year: 2020
Book Volume: 9
Journal Issue: 6
DOI: 10.3390/cells9061395
Distinctly organized microtubule networks contribute to the function of differentiated cell types such as neurons, epithelial cells, skeletal myotubes, and cardiomyocytes. In striated (i.e. skeletal and cardiac) muscle cells, the nuclear envelope acts as the dominant microtubule-organizing center (MTOC) and the function of the centrosome-the canonical MTOC of mammalian cells-is attenuated, a common feature of differentiated cell types. We summarize the mechanisms known to underlie MTOC formation at the nuclear envelope, discuss the significance of the nuclear envelope MTOC for muscle function and cell cycle progression, and outline potential mechanisms of centrosome attenuation.
APA:
Becker, R., Leone, M., & Engel, F. (2020). Microtubule Organization in Striated Muscle Cells. Cells, 9(6). https://doi.org/10.3390/cells9061395
MLA:
Becker, Robert, Marina Leone, and Felix Engel. "Microtubule Organization in Striated Muscle Cells." Cells 9.6 (2020).
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