Risk factors for complicated lymphadenitis caused by nontuberculous mycobacteria in children

Kuntz M, Kohlfürst DS, Feiterna-Sperling C, Krüger R, Baumann U, Buchtala L, Elling R, Grote V, Hübner J, Hufnagel M, Kaiser-Labusch P, Liese J, Otto EM, Rose MA, Schneider C, Schuster V, Seidl M, Sommerburg O, Vogel M, von Bernuth H, Weiß M, Zimmermann T, Nieters A, Zenz W, Henneke P (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Emerging Infectious Diseases U.S. National Center for Infectious Diseases

Book Volume: 26

Pages Range: 579-586

Journal Issue: 3

DOI: 10.3201/eid2603.191388

Abstract

Nontuberculous mycobacteria (NTM) are an emerging cause of infections, including chronic lymphadenitis in children. To identify risk factors for NTM lymphadenitis, particularly complicated disease, we collected epidemiologic, clinical, and microbiological data on 138 cases of NTM lymphadenitis in children across 13 centers in Germany and Austria. We assessed lifestyle factors but did not identify specific risk behaviors. We noted that more cases of NTM lymphadenitis occurred during cold months than during warm months. Moreover, we noted female sex and age <5.5 years as potential risk factors. Complete extirpation of the affected lymph node appeared to be the best therapeutic measure. We integrated the study data to develop a simple risk score to predict unfavorable clinical outcomes for NTM lymphadenitis.

Authors with CRIS profile

Theodor Zimmermann Medizinische Fakultät

Involved external institutions

Klinikum der Universität München DE Germany (DE) Albert-Ludwigs-Universität Freiburg DE Germany (DE) Medizinische Hochschule Hannover (MHH) / Hannover Medical School DE Germany (DE) Charité - Universitätsmedizin Berlin DE Germany (DE) Goethe-Universität Frankfurt am Main DE Germany (DE) Klinikum Bremen-Mitte DE Germany (DE) Universität Leipzig DE Germany (DE) Medizinische Universität Graz AT Austria (AT) Ruprecht-Karls-Universität Heidelberg DE Germany (DE) Heinrich-Heine-Universität Düsseldorf DE Germany (DE) Universitätsklinikum Würzburg DE Germany (DE)

How to cite

APA:

Kuntz, M., Kohlfürst, D.S., Feiterna-Sperling, C., Krüger, R., Baumann, U., Buchtala, L.,... Henneke, P. (2020). Risk factors for complicated lymphadenitis caused by nontuberculous mycobacteria in children. Emerging Infectious Diseases, 26(3), 579-586. https://doi.org/10.3201/eid2603.191388

MLA:

Kuntz, Martin, et al. "Risk factors for complicated lymphadenitis caused by nontuberculous mycobacteria in children." Emerging Infectious Diseases 26.3 (2020): 579-586.

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