Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017) - Part 1 with Introduction, Screening and the Pathology of Cervical Dysplasia

Hillemanns P, Friese K, Dannecker C, Klug S, Seifert U, Iftner T, Haedicke J, Loening T, Horn L, Schmidt D, Ikenberg H, Steiner M, Freitag U, Siebert U, Sroczynski G, Sauerbrei W, Beckmann M, Gebhardt M, Friedrich M, Muenstedt K, Schneider A, Kaufmann A, Petry KU, Schaefer APA, Pawlita M, Weis J, Mehnert A, Fehr M, Grimm C, Reich O, Arbyn M, Kleijnen J, Wesselmann S, Nothacker M, Follmann M, Langer T, Jentschke M (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 79

Pages Range: 148-159

Journal Issue: 2

DOI: 10.1055/a-0818-5440

Abstract

Annual opportunistic screening for cervical carcinoma has been carried out in Germany since 1971. The creation of this S3 guideline meets an important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as the guideline aims to provide important information and support for planned organized screening for cervical cancer in Germany. With the financial support of German Cancer Aid, 21 professional societies developed evidence-based statements and recommendations (classified using the GRADE system) for the screening, management and treatment of precancerous conditions of the cervix. Two independent scientific institutes compiled systematic reviews for this guideline. The first part of this short summary presents the pathological basis and considers various questions related to screening for cervical cancer. As also reported in earlier reviews, the meta-analysis by Kleijnen Systematic Reviews showed that HPV-based screening offers better protection against invasive cervical cancer compared to cytology-based screening. The authors of this guideline therefore recommend - in accordance with the guideline of the Joint National Committee of Germany (Gemeinsamer Bundesauschuss, G-BA) - that women aged 35 and above should be examined at regular intervals (at least every 3 years) and undergo HPV-based screening. Co-testing can also be carried out. Women between the ages of 20 and 35 should have cytological screening every 2 years.

Authors with CRIS profile

Involved external institutions

Medizinische Hochschule Hannover (MHH) / Hannover Medical School Germany (DE) MVZ für Zytologie und Molekularbiologie Frankfurt GbR (CytoMol) Germany (DE) Deutsche Krebsgesellschaft (DKG) Germany (DE) Klinikum Wolfsburg Germany (DE) Technische Universität München (TUM) Germany (DE) Klinikum der Universität München Germany (DE) Universitätsklinikum Tübingen Germany (DE) Ortenau Klinikum Germany (DE) Kleijnen Systematic Reviews United Kingdom (GB) Universitätsklinikum Leipzig Germany (DE) HELIOS Kliniken Germany (DE) UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik GmbH Austria (AT) Technische Universität Dresden Germany (DE) Klinik Bad Trissl Germany (DE) Spital Thurgau AG Switzerland (CH) Deutsches Krebsforschungszentrum (DKFZ) Germany (DE) Charité - Universitätsmedizin Berlin Germany (DE) Albertinen-Krankenhaus Germany (DE) Sciensano Belgium (BE) Universitätsklinikum Freiburg Germany (DE) Privatklinik Graz Ragnitz Austria (AT) AWMF-Institut für Medizinisches Wissensmanagement (AWMF-IMWi) Germany (DE)

How to cite

APA:

Hillemanns, P., Friese, K., Dannecker, C., Klug, S., Seifert, U., Iftner, T.,... Jentschke, M. (2019). Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017) - Part 1 with Introduction, Screening and the Pathology of Cervical Dysplasia. Geburtshilfe und Frauenheilkunde, 79(2), 148-159. https://doi.org/10.1055/a-0818-5440

MLA:

Hillemanns, Peter, et al. "Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017) - Part 1 with Introduction, Screening and the Pathology of Cervical Dysplasia." Geburtshilfe und Frauenheilkunde 79.2 (2019): 148-159.

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