Step Rate and Worsening of Patellofemoral and Tibiofemoral Joint Osteoarthritis in Women and Men: The Multicenter Osteoarthritis Study
Hart HF, Gross KD, Crossley KM, Barton CJ, Felson DT, Guermazi A, Roemer F, Segal NA, Lewis CE, Nevitt MC, Stefanik JJ (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 72
Pages Range: 107-113
Journal Issue: 1
DOI: 10.1002/acr.23864
Abstract
Objective: To determine the association of self-selected walking step rate with worsening of cartilage damage in the patellofemoral (PF) joint and tibiofemoral (TF) joint compartments at a 2-year follow-up visit. Methods: The Multicenter Osteoarthritis Study (MOST) is a prospective cohort of men and women with or at risk of knee osteoarthritis. Self-selected step rate was measured using an instrumented GAITRite walkway (CIR Systems) at the 60-month visit. Cartilage damage was semiquantitatively graded on magnetic resonance images at the 60- and 84-month visits in the medial and lateral PF and TF compartments. Step rate was divided into quartiles, and logistic regression was used to determine the association of step rate with the risk of worsening cartilage damage in men and women separately. Analyses were adjusted for age, body mass index, and knee injury/surgery. Results: A total of 1,089 participants were included. Mean ± SD age was 66.9 ± 7.5 years, mean ± SD body mass index was 29.6 ± 4.7 kg/m2, and 62.3% of the participants were women. Women with the lowest step rate had increased risk of lateral PF (risk ratio [RR] 2.1 [95% confidence interval (95% CI) 1.1–3.8]) and TF (RR 1.8 [95% CI 1.1–2.9]) cartilage damage worsening 2 years later compared to those with the highest step rate. Men with the lowest step rate had increased risk of medial TF cartilage damage worsening 2 years later (RR 2.1 [95% CI 1.1–3.9]). Conclusion: Lower step rate was associated with increased risk of cartilage damage worsening in the lateral PF and TF compartments in women and worsening medial TF joint damage in men. Future research is necessary to understand the influence of step rate manipulation on joint biomechanics in women and men.
Authors with CRIS profile
Involved external institutions
Massachusetts General Hospital
United States (USA) (US)
University of Kansas Medical Center
United States (USA) (US)
University of California San Francisco (UCSF)
United States (USA) (US)
Boston University
United States (USA) (US)
La Trobe University
Australia (AU)
Northeastern University
United States (USA) (US)
University of Alabama at Birmingham (UAB)
United States (USA) (US)
United States (USA) (US)
University of Kansas Medical Center
United States (USA) (US)
University of California San Francisco (UCSF)
United States (USA) (US)
Boston University
United States (USA) (US)
La Trobe University
Australia (AU)
Northeastern University
United States (USA) (US)
University of Alabama at Birmingham (UAB)
United States (USA) (US)
How to cite
APA:
Hart, H.F., Gross, K.D., Crossley, K.M., Barton, C.J., Felson, D.T., Guermazi, A.,... Stefanik, J.J. (2020). Step Rate and Worsening of Patellofemoral and Tibiofemoral Joint Osteoarthritis in Women and Men: The Multicenter Osteoarthritis Study. Arthritis & Rheumatism-Arthritis Care & Research, 72(1), 107-113. https://doi.org/10.1002/acr.23864
MLA:
Hart, Harvi F., et al. "Step Rate and Worsening of Patellofemoral and Tibiofemoral Joint Osteoarthritis in Women and Men: The Multicenter Osteoarthritis Study." Arthritis & Rheumatism-Arthritis Care & Research 72.1 (2020): 107-113.
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