Phosphate glass fibres with therapeutic ions release capability–a review

Lapa A, Cresswell M, Jackson P, Boccaccini AR (2020)

Publication Type: Journal article, Review article

Publication year: 2020


Book Volume: 119

Pages Range: 1-14

Journal Issue: 1

DOI: 10.1080/17436753.2018.1564413


Phosphate-based glasses (PBG) have low melting temperatures and can be obtained by melt-quenching and sol-gel methods. The most significant characteristic of PBG is their ability to dissolve completely in aqueous solution within different timeframes. This solubility can reduce the need for revision surgeries and makes PBG well-suited for soft tissue regeneration. Phosphate glass fibres (PGF) due to their geometry and volume–surface area ratio are the subject of a growing number of studies on resorbable composites. Medical applications include bone fixation devices, nerve tissue scaffolds and wound healing. PBG can be doped with various ions to enhance their biological, chemical and structural properties allowing the preparation of fibres with designed properties and with the ability to release biologically active ions upon degradation. The aim of this review is to look in detail at the influence of different dopants on PGF behaviour, both at a structural and biological level.

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Lapa, A., Cresswell, M., Jackson, P., & Boccaccini, A.R. (2020). Phosphate glass fibres with therapeutic ions release capability–a review. Advances in Applied Ceramics, 119(1), 1-14.


Lapa, Agata, et al. "Phosphate glass fibres with therapeutic ions release capability–a review." Advances in Applied Ceramics 119.1 (2020): 1-14.

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