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Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window

Meng X, Du Y, Wang R, Li Z, Zhu S, Wu H, Li C, Chen W, Nie S, Ren Q, Lu Y (2019)

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Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 452

Pages Range: 417-421

DOI: 10.1016/j.optcom.2019.05.017

Abstract

The Cherenkov radiation induced by megavolt X-ray beams of a medical linear accelerator is highly intense in blue and ultraviolet lights. This poses a challenge for in vivo imaging, which favors longer wavelengths. However, using quantum dots with a large Stokes shift, we converted the Cherenkov photons to fluorescent photons in the second near-infrared (NIR-II) window. A system was designed to provide shielding for the NIR-II camera, and high quality NIR-II CELI signal was acquired. The NIR-II CELI of X-ray beams was shown at various depths, and the condition to trigger it was also studied. Animal experiments showed this technique could visualize the delivery of X-ray radiation in mice qualitatively. We concluded that CELI induced by megavolt X-ray beams in the NIR-II window possesses a great potential as a quality control tool in radiotherapy.

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How to cite

APA:

Meng, X., Du, Y., Wang, R., Li, Z., Zhu, S., Wu, H.,... Lu, Y. (2019). Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window. Optics Communications, 452, 417-421. https://dx.doi.org/10.1016/j.optcom.2019.05.017

MLA:

Meng, Xiangxi, et al. "Cherenkov excited luminescence imaging induced by megavolt X-ray beams in the second near-infrared window." Optics Communications 452 (2019): 417-421.

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