Changes in Corneal Biomechanical Properties After Descemet Membrane Endothelial Keratoplasty

Siggel R, Christofi E, Giasoumi F, Adler W, Siebelmann S, Bachmann B, Cursiefen C, Heindl LM (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Cornea Lippincott, Williams & Wilkins

Book Volume: 38

Pages Range: 964-969

Journal Issue: 8

DOI: 10.1097/ICO.0000000000001986

Abstract

PURPOSE: To evaluate the course of corneal biomechanical properties (corneal hysteresis and corneal resistance factor) after Descemet membrane endothelial keratoplasty (DMEK) in patients with Fuchs endothelial dystrophy (FECD). METHODS: In this prospective study, we consecutively included 49 patients with FECD with an indication for DMEK. Central corneal thickness, measured using the Oculus Pentacam, and corneal hysteresis (CH) and corneal resistance factor (CRF), both measured using the Reichert Ocular Response Analyzer, were examined preoperatively, 3 months, and 6 months after DMEK. RESULTS: CH was significantly increased 6 months postoperatively (8.66 ± 2.50 mm Hg) compared with preoperative baseline (7.43 ± 1.56 mm Hg). Preoperative CRF (7.89 ± 1.68 mm Hg) increased significantly 6 months after DMEK (8.49 ± 1.71 mm Hg). Preoperative central corneal thickness showed a significant decrease from 629 ± 58 μm to 550 ± 40 μm after 3 months and 535 ± 40 μm after 6 months postoperatively. CONCLUSIONS: DMEK affects both measured corneal biomechanical properties in patients with FECD: CH and CRF. This has to be taken into account for the accuracy of intraocular pressure measurements.

Authors with CRIS profile

Werner Adler Lehrstuhl für Biometrie und Epidemiologie

Involved external institutions

Universität zu Köln DE Germany (DE)

How to cite

APA:

Siggel, R., Christofi, E., Giasoumi, F., Adler, W., Siebelmann, S., Bachmann, B.,... Heindl, L.M. (2019). Changes in Corneal Biomechanical Properties After Descemet Membrane Endothelial Keratoplasty. Cornea, 38(8), 964-969. https://doi.org/10.1097/ICO.0000000000001986

MLA:

Siggel, Robert, et al. "Changes in Corneal Biomechanical Properties After Descemet Membrane Endothelial Keratoplasty." Cornea 38.8 (2019): 964-969.

BibTeX: Download