Misleading debate – incidental findings in genomic research
Schuol S (2017)
Publication Language: English
Publication Type: Conference contribution, Conference Contribution
Publication year: 2017
Event location: TILPS - Tilburg University
Abstract
Since mutations with health relevance exist (2% in population with European ancestry - Amendola et al. 2015) why are these mutations not found incidentally? In contrast to med imaging, even a trained researcher cannot “see” IFs in genomic sequence. Owing to the complexity of genomic data, bioinformatic filters are necessary that avoid detection of incidental findings.
General conclusion: The debate on IFs in genomic research was a waste of cognitive, financial and psychological resources. Two steps to prevent such debates in future: 1. Early solution-development for plausible scenarios. 2. Then when empirical data is available – evaluation whether these projections remain true. The scenario has to be substantiated or, if necessary, corrected.
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How to cite
APA:
Schuol, S. (2017). Misleading debate – incidental findings in genomic research. In Proceedings of the Perspectives on scientific errors. TILPS - Tilburg University, NL.
MLA:
Schuol, Sebastian. "Misleading debate – incidental findings in genomic research." Proceedings of the Perspectives on scientific errors, TILPS - Tilburg University 2017.
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