A multidisciplinary systematic review of the treatment for chronic idiopathic tinnitus

Zenner HP, Delb W, Kroener-Herwig B, Jaeger B, Peroz I, Hesse G, Mazurek B, Goebel G, Gerloff C, Trollmann R, Biesinger E, Seidler H, Langguth B (2017)

Publication Type: Journal article

Publication year: 2017


Book Volume: 274

Pages Range: 2079-2091

Journal Issue: 5

DOI: 10.1007/s00405-016-4401-y


The majority of tinnitus patients are affected by chronic idiopathic tinnitus, and almost 60 different treatment modalities have been reported. The present study is a multidisciplinary systematic analysis of the evidence for the different forms of treatment for chronic tinnitus. The results are used to form the basis of an S3 guideline. A systematic search was carried out in PubMed and the Cochrane Library. The basis for presenting the level of evidence was the evidence classification of the Oxford Centre of Evidence-based Medicine. Whenever available, randomised controlled trials were given preference for discussing therapeutic issues. All systematic reviews and meta-analyses were assessed for their methodological quality, and effect size was taken into account. As the need for patient counselling is self-evident, specific tinnitus counselling should be performed. Due to the high level of evidence, validated tinnitus-specific, cognitive behavioural therapy is strongly recommended. In addition, auditory therapeutic measures can be recommended for the treatment of concomitant hearing loss and comorbidities; those should also be treated with drugs whenever appropriate. In particular, depression should be treated, with pharmacological support if necessary. If needed, psychiatric treatment should also be given on a case-by-case basis. With simultaneous deafness or hearing loss bordering on deafness, a CI can also be indicated. For auditory therapeutic measures, transcranial magnetic or direct current stimulation and specific forms of acoustic stimulation (noiser/masker, retraining therapy, music, and coordinated reset) for the treatment of chronic tinnitus the currently available evidence is not yet sufficient for supporting their recommendation.

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Zenner, H.-P., Delb, W., Kroener-Herwig, B., Jaeger, B., Peroz, I., Hesse, G.,... Langguth, B. (2017). A multidisciplinary systematic review of the treatment for chronic idiopathic tinnitus. European Archives of Oto-Rhino-Laryngology, 274(5), 2079-2091. https://doi.org/10.1007/s00405-016-4401-y


Zenner, Hans-Peter, et al. "A multidisciplinary systematic review of the treatment for chronic idiopathic tinnitus." European Archives of Oto-Rhino-Laryngology 274.5 (2017): 2079-2091.

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