Automated setup for ex vivo larynx experiments

Birk V, Döllinger M, Sutor A, Berry DA, Gedeon D, Traxdorf M, Wendler O, Bohr C, Kniesburges S (2017)


Publication Type: Journal article

Publication year: 2017

Journal

Book Volume: 141

Pages Range: 1349-1359

Journal Issue: 3

DOI: 10.1121/1.4976085

Abstract

Ex vivo larynx experiments are limited in time due to degeneration of the laryngeal tissues. In order to acquire a significant and comparable amount of data, automatization of current manual experimental procedures is desirable. A computer controlled, electro-mechanical setup was developed for time-dependent variation of specific physiological parameters, including adduction and elongation level of the vocal folds and glottal flow. The setup offers a standardized method to induce defined forces on the laryngeal cartilages. Furthermore, phonation onset is detected automatically and the subsequent measurement procedure is automated and standardized to improve the efficiency of the experimental process. The setup was validated using four ex vivo porcine larynges, whereas each validation measurement series was executed with one separate larynx. Altogether 31 single measurements were undertaken, which can be summed up to a total experimental time of about 4 min. Vocal fold elongation and adduction lead both to an increase in fundamental frequency and subglottal pressure. Measurement procedures like applying defined subglottal pressure steps and onset-offset detection were reliably executed. The setup allows for a computer-based parameter control, which enables fast experimental execution over a wide range of laryngeal configurations. This maximizes the number of measurements and reduces personal effort compared with manual procedures.

Authors with CRIS profile

Involved external institutions

How to cite

APA:

Birk, V., Döllinger, M., Sutor, A., Berry, D.A., Gedeon, D., Traxdorf, M.,... Kniesburges, S. (2017). Automated setup for ex vivo larynx experiments. Journal of the Acoustical Society of America, 141(3), 1349-1359. https://doi.org/10.1121/1.4976085

MLA:

Birk, Veronika, et al. "Automated setup for ex vivo larynx experiments." Journal of the Acoustical Society of America 141.3 (2017): 1349-1359.

BibTeX: Download