Noninvasive Fractional Flow Reserve Derived From Coronary CT Angiography: Clinical Data and Scientific Principles

Min JK, Taylor CA, Achenbach S, Koo BK, Leipsic J, Norgaard BL, Pijls NJ, De Bruyne B (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Journal of the American College of Cardiology : Cardiovascular imaging Elsevier

Book Volume: 8

Pages Range: 1209-22

Journal Issue: 10

DOI: 10.1016/j.jcmg.2015.08.006

Abstract

Fractional flow reserve derived from coronary computed tomography angiography enables noninvasive assessment of the hemodynamic significance of coronary artery lesions and coupling of the anatomic severity of a coronary stenosis with its physiological effects. Since its initial demonstration of feasibility of use in humans in 2011, a significant body of clinical evidence has developed to evaluate the diagnostic performance of coronary computed tomography angiography-derived fractional flow reserve compared with an invasive fractional flow reserve reference standard. The purpose of this paper was to describe the scientific principles and to review the clinical data of this technology recently approved by the U.S. Food and Drug Administration.

Authors with CRIS profile

Stephan Achenbach Lehrstuhl für Innere Medizin II

Additional Organisation(s)

Department of Medicine 2 – Cardiology and Angiology

Involved external institutions

Cornell University US United States (USA) (US) HeartFlow Inc. US United States (USA) (US) Seoul National University (SNU) / 서울대학교 KR Korea, Republic of (KR) University of British Columbia CA Canada (CA) Catharina Hospital / Catharina Ziekenhuis NL Netherlands (NL) Onze-Lieve-Vrouwziekenhuis (OLV Ziekenhuis, OLVZ) BE Belgium (BE)

How to cite

APA:

Min, J.K., Taylor, C.A., Achenbach, S., Koo, B.K., Leipsic, J., Norgaard, B.L.,... De Bruyne, B. (2015). Noninvasive Fractional Flow Reserve Derived From Coronary CT Angiography: Clinical Data and Scientific Principles. Journal of the American College of Cardiology : Cardiovascular imaging, 8(10), 1209-22. https://doi.org/10.1016/j.jcmg.2015.08.006

MLA:

Min, James K., et al. "Noninvasive Fractional Flow Reserve Derived From Coronary CT Angiography: Clinical Data and Scientific Principles." Journal of the American College of Cardiology : Cardiovascular imaging 8.10 (2015): 1209-22.

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