Simplified design of steady-state recycling chromatography under ideal and nonideal conditions

Kaspereit M, Sainio T (2011)


Publication Language: English

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2011

Journal

Publisher: Elsevier

Book Volume: 66

Pages Range: 5428-5438

Journal Issue: 21

DOI: 10.1016/j.ces.2011.07.058

Abstract

In a recent contribution a design method for steady-state recycling chromatography in the so-called mixed-recycle mode (MR-SSR) has been proposed by Sainio and Kaspereit (2009). The method holds under ideal, dispersion-free conditions for chromatographic systems with competitive Langmuir adsorption isotherms. Here this approach is extended to practically relevant nonideal conditions with significant dispersive effects and convex-upward adsorption isotherms in general. The developed shortcut design method allows designing MR-SSR processes based on a simple procedure applied to a single conventional chromatogram. The method is validated experimentally for the separation of two cycloketones on a polymeric stationary phase. The performance of the MR-SSR process is compared to batch chromatography by means of a simulation study. © 2011 Elsevier Ltd.

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How to cite

APA:

Kaspereit, M., & Sainio, T. (2011). Simplified design of steady-state recycling chromatography under ideal and nonideal conditions. Chemical Engineering Science, 66(21), 5428-5438. https://doi.org/10.1016/j.ces.2011.07.058

MLA:

Kaspereit, Malte, and Tuomo Sainio. "Simplified design of steady-state recycling chromatography under ideal and nonideal conditions." Chemical Engineering Science 66.21 (2011): 5428-5438.

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