Hypoxia and hypoxia-inducible factors in myeloid cell-driven host defense and tissue homeostasis

Jantsch J, Schoedel J (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Immunobiology Elsevier

Book Volume: 220

Pages Range: 305-314

Journal Issue: 2

DOI: 10.1016/j.imbio.2014.09.009

Abstract

The impact of tissue oxygenation and hypoxia on immune cells has been recognized as a major determinant of host defense and tissue homeostasis. In this review, we will summarize the available data on tissue oxygenation in inflamed and infected tissue and the effect of low tissue oxygenation on myeloid cell function. Furthermore, we will highlight effects of the master regulators of the cellular hypoxic response, hypoxia-inducible transcription factors (HIF), in myeloid cells in antimicrobial defense and tissue homeostasis.

Involved external institutions

Universitätsklinikum Regensburg DE Germany (DE)

How to cite

APA:

Jantsch, J., & Schoedel, J. (2015). Hypoxia and hypoxia-inducible factors in myeloid cell-driven host defense and tissue homeostasis. Immunobiology, 220(2), 305-314. https://doi.org/10.1016/j.imbio.2014.09.009

MLA:

Jantsch, Jonathan, and Johannes Schoedel. "Hypoxia and hypoxia-inducible factors in myeloid cell-driven host defense and tissue homeostasis." Immunobiology 220.2 (2015): 305-314.

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