Phenylpiperazinylmethylindolecarboxylates and Derivatives as Selective D4-Ligands

Troschütz R, Gmeiner P, Hübner H (2002)

Publication Type: Journal article

Publication year: 2002

Journal

Bioorganic & Medicinal Chemistry Elsevier

Publisher: Elsevier

Book Volume: 10

Pages Range: 1671-1679

DOI: 10.1016/S0968-0896(02)00042-1

Abstract

Novel phenylpiperazinylmethylindolecarboxylates were synthesized for evaluation as potential D4-ligands. Test compounds showed high affinity for the human dopamine D4 receptor and great selectivity over the other receptor subtypes. Intrinsic effects of indole derivatives, which indicated most promising binding properties, were investigated in a mitogenesis assay. © 2002 Elsevier Science Ltd. All rights reserved.

Authors with CRIS profile

Reinhard Troschütz Naturwissenschaftliche Fakultät Peter Gmeiner Lehrstuhl für Pharmazeutische Chemie Harald Hübner Lehrstuhl für Pharmazeutische Chemie

How to cite

APA:

Troschütz, R., Gmeiner, P., & Hübner, H. (2002). Phenylpiperazinylmethylindolecarboxylates and Derivatives as Selective D4-Ligands. Bioorganic & Medicinal Chemistry, 10, 1671-1679. https://doi.org/10.1016/S0968-0896(02)00042-1

MLA:

Troschütz, Reinhard, Peter Gmeiner, and Harald Hübner. "Phenylpiperazinylmethylindolecarboxylates and Derivatives as Selective D4-Ligands." Bioorganic & Medicinal Chemistry 10 (2002): 1671-1679.

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