Gmeiner P (1999)
Publication Type: Journal article
Publication year: 1999
Publisher: Govi Verlag GMBH
Book Volume: 54
Pages Range: 248-250
Employing the dopamine autoreceptor agonist (-)-3-PPP (3) as well as the cholinergic receptor ligands 4 and 5 as lead compounds the 3- pyrrolidinylisoxazoles 2a,b as well as its optical antipodes ent-2a,b were synthesized from (R)-aspartic acid (6) and (S)-aspartic acid (ent-6), respectively. Pharmacological properties of the target compounds were evaluated employing dopamine D2 receptor binding studies and functional experiments on muscarinic M2 receptors.
APA:
Gmeiner, P. (1999). Ex-Chiral Pool Synthesis and Pharmacological Aspects of 3-Pyrrolidinylisoxazoles. Pharmazie, 54, 248-250.
MLA:
Gmeiner, Peter. "Ex-Chiral Pool Synthesis and Pharmacological Aspects of 3-Pyrrolidinylisoxazoles." Pharmazie 54 (1999): 248-250.
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