Diethoxymethyl: A Useful Nitrogen-Protecting Group for Lactams and Amides

Gmeiner P (1995)


Publication Type: Journal article

Publication year: 1995

Journal

Publisher: Thieme Publishing / Georg Thieme Verlag

Pages Range: 168-170

Abstract

Treatment of the lactams 3a-e and the amide 3f with triethyl orthoformate leads to the N-diethoxymethyl substituted derivatives 4a-f. Additionally, the indolinones 3a and 3b can react at the lactam α-position to give the reaction products 2 and 5, respectively. The diethoxymethyl group can be easily removed by subsequent treatment with trifluoroacetic acid and NaOH.

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How to cite

APA:

Gmeiner, P. (1995). Diethoxymethyl: A Useful Nitrogen-Protecting Group for Lactams and Amides. Synthesis-Stuttgart, 168-170.

MLA:

Gmeiner, Peter. "Diethoxymethyl: A Useful Nitrogen-Protecting Group for Lactams and Amides." Synthesis-Stuttgart (1995): 168-170.

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