Ultrasonic elasticity determination of 45S5 Bioglass®-based scaffolds: Influence of polymer coating and crosslinking treatment

Li W, Pastrama MI, Ding Y, Zheng K, Hellmich C, Boccaccini AR (2014)

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2014

Journal

Journal of the Mechanical Behavior of Biomedical Materials Elsevier

Publisher: Elsevier

Book Volume: 40

Pages Range: 85-94

DOI: 10.1016/j.jmbbm.2014.08.010

Abstract

Highly porous 45S5 Bioglass-based scaffolds with interconnected pore structure are promising candidates for bone tissue engineering due to their bioactivity, biocompatibility, osteogenic and angiogenic effects. In the present study, to ensure the mechanical competence of the 45S5 Bioglass-based scaffolds, their stiffness was adjusted by applying polymer coatings and further crosslinking treatment. A non-destructive ultrasonic technique was used to determine the stiffness of the scaffolds. The stiffness of uncoated scaffolds was shown to increase by applying polymer coatings, and a further increase was achieved by crosslinking the used polymer coatings. All uncoated and polymer-coated scaffolds were confirmed to exhibit stiffness values in the range of reported values in the literature for cancellous bone. A statistical evaluation of combined multiscale ultrasound-nanoindentation measurements indicated that the stiffness of the coated scaffold is directly dependent on the stiffness of the polymer coating.

Authors with CRIS profile

Wei Li Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Yaping Ding Lehrstuhl für Werkstoffwissenschaften (Polymerwerkstoffe) (LSP) Kai Zheng Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Technische Universität Wien / Vienna University of Technology AT Austria (AT)

How to cite

APA:

Li, W., Pastrama, M.-I., Ding, Y., Zheng, K., Hellmich, C., & Boccaccini, A.R. (2014). Ultrasonic elasticity determination of 45S5 Bioglass®-based scaffolds: Influence of polymer coating and crosslinking treatment. Journal of the Mechanical Behavior of Biomedical Materials, 40, 85-94. https://doi.org/10.1016/j.jmbbm.2014.08.010

MLA:

Li, Wei, et al. "Ultrasonic elasticity determination of 45S5 Bioglass®-based scaffolds: Influence of polymer coating and crosslinking treatment." Journal of the Mechanical Behavior of Biomedical Materials 40 (2014): 85-94.

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