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2-Dibenzylaminobutane-1,4-diol: An Effective Chiral Building Block for the Synthesis of 1,2-Amino Alcohols

Gmeiner P (1995)

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Publication Type: Journal article

Publication year: 1995

Journal

Publisher: Thieme Publishing / Georg Thieme Verlag

Pages Range: 83-86

Abstract

Regioselective activation and protection of the chiral building block 1, readily available from L-aspartic acid, leads to the key intermediate 8. Employing classical nucleophiles, heterocyclic anions or organocuprates, 8 could be transformed into the displacement products 9. Finally, hydrolysis affords the homochiral 1,2-amino alcohols 4 in 48-77% yield (based on 8).

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How to cite

APA:

Gmeiner, P. (1995). 2-Dibenzylaminobutane-1,4-diol: An Effective Chiral Building Block for the Synthesis of 1,2-Amino Alcohols. Synthesis-Stuttgart, 83-86.

MLA:

Gmeiner, Peter. "2-Dibenzylaminobutane-1,4-diol: An Effective Chiral Building Block for the Synthesis of 1,2-Amino Alcohols." Synthesis-Stuttgart (1995): 83-86.

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