Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases

De With K, Allerberger F, Amann S, Apfalter P, Brodt HR, Eckmanns T, Fellhauer M, Geiss HK, Janata O, Krause R, Lemmen S, Meyer E, Mittermayer H, Porsche U, Presterl E, Reuter S, Sinha B, Strauss R, Wechsler-Foerdoes A, Wenisch C, Kern WV (2016)

Publication Type: Journal article

Publication year: 2016

Journal

Book Volume: 44

Pages Range: 395-439

Journal Issue: 3

DOI: 10.1007/s15010-016-0885-z

Abstract

In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed by the German Society for Infectious Diseases in association with the following societies, associations and institutions: German Society of Hospital Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian Society for Infectious Diseases and Tropical Medicine, Austrian Society for Antimicrobial Chemotherapy, Robert Koch Institute.A structured literature research was performed in the databases EMBASE, BIOSIS, MEDLINE and The Cochrane Library from January 2006 to November 2010 with an update to April 2012 (MEDLINE and The Cochrane Library). The grading of recommendations in relation to their evidence is according to the AWMF Guidance Manual and Rules for Guideline Development.The guideline provides the grounds for rational use of antibiotics in hospital to counteract antimicrobial resistance and to improve the quality of care of patients with infections by maximising clinical outcomes while minimising toxicity. Requirements for a successful implementation of ABS programmes as well as core and supplemental ABS strategies are outlined. The German version of the guideline was published by the German Association of the Scientific Medical Societies (AWMF) in December 2013.

Involved external institutions

Albert-Ludwigs-Universität Freiburg Germany (DE) Sozialmedizinisches Zentrum Süd - Kaiser-Franz-Josef-Spital Austria (AT) Krankenanstalt Rudolfstiftung Austria (AT) University of Groningen / Rijksuniversiteit Groningen Netherlands (NL) Klinikum Leverkusen Germany (DE) Medizinische Universität Wien Austria (AT) Salzburger Landeskliniken (SALK) Austria (AT) Ordensklinikum Linz - Elisabethinen Austria (AT) Charité - Universitätsmedizin Berlin Germany (DE) Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen Germany (DE) Sozialmedizinisches Zentrum Ost – Donauspital (SMZ Ost) Austria (AT) Sana Kliniken AG Germany (DE) Schwarzwald-Baar Klinikum Germany (DE) Robert Koch-Institut (RKI) Germany (DE) Goethe-Universität Frankfurt am Main Germany (DE) Städtisches Klinikum München Germany (DE) Österreichische Agentur für Gesundheit und Ernährungssicherheit (AGES) Austria (AT) Technische Universität Dresden Germany (DE)

How to cite

APA:

De With, K., Allerberger, F., Amann, S., Apfalter, P., Brodt, H.-R., Eckmanns, T.,... Kern, W.V. (2016). Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases. Infection, 44(3), 395-439. https://doi.org/10.1007/s15010-016-0885-z

MLA:

De With, K., et al. "Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases." Infection 44.3 (2016): 395-439.

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