Benefit of Contrast-Enhanced Ultrasound (CEUS) in the Follow-Up Care of Patients with Colon Cancer: A Prospective Multicenter Study

Bernatik T, Schuler A, Kunze G, Mauch M, Dietrich CF, Dirks K, Pachmann C, Boerner N, Fellermann K, Menzel J, Strobel D (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Ultraschall in der Medizin Georg Thieme Verlag

Book Volume: 36

Pages Range: 590-3

Journal Issue: 6

DOI: 10.1055/s-0041-107833

Abstract

According to the German guidelines on colorectal cancer, unenhanced ultrasound is recommended for follow-up. On the other hand, ultrasound and radiology societies specify the use of contrast-enhanced ultrasound for ruling out liver metastases. Studies focusing on the follow-up of cancer patients are lacking. The goal of this multicenter study initiated by the German Ultrasound Society (DEGUM) was to determine the potential benefit of contrast-enhanced ultrasound in the follow-up of patients with colon cancer.Follow-up patients with colon cancer (UICC > IIa) were investigated. As scheduled according to the German guidelines, unenhanced ultrasound was performed followed by contrast-enhanced ultrasound. All liver lesions were recorded. In case of additional metastases detected on contrast-enhanced ultrasound, contrast-enhanced CT, MRI or biopsy was performed to confirm additional liver metastases.A total of 45 liver metastases were detected in 26/290 patients (= 9 %) using unenhanced ultrasound. A further 28 metastases were detected on contrast-enhanced ultrasound in these 26 patients. In 18 patients showing no liver metastases, 40 additional metastases were detected on unenhanced ultrasound. This means that 44 patients with a total of 113 liver metastases were detected on contrast-enhanced ultrasound (p = 0.0006).Contrast-enhanced ultrasound should be recommended in the follow-up of patients with colon cancer in addition to unenhanced ultrasound - the up-to-date standard.

Authors with CRIS profile

Deike Strobel Medizinische Fakultät

Additional Organisation(s)

Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology

Involved external institutions

SRH Kreiskrankenhaus Sigmaringen DE Germany (DE) Israelitisches Krankenhaus Hamburg DE Germany (DE) Alb Fils Kliniken DE Germany (DE) Kreisklinik Ebersberg DE Germany (DE) Caritas-Krankenhaus Bad Mergentheim gemeinnützige GmbH DE Germany (DE) MED Facharztzentrum DE Germany (DE) Universität zu Lübeck DE Germany (DE) Klinikum Ingolstadt DE Germany (DE) Rems-Murr-Kliniken DE Germany (DE) Schwarzwald-Baar Klinikum DE Germany (DE)

How to cite

APA:

Bernatik, T., Schuler, A., Kunze, G., Mauch, M., Dietrich, C.F., Dirks, K.,... Strobel, D. (2015). Benefit of Contrast-Enhanced Ultrasound (CEUS) in the Follow-Up Care of Patients with Colon Cancer: A Prospective Multicenter Study. Ultraschall in der Medizin, 36(6), 590-3. https://doi.org/10.1055/s-0041-107833

MLA:

Bernatik, T., et al. "Benefit of Contrast-Enhanced Ultrasound (CEUS) in the Follow-Up Care of Patients with Colon Cancer: A Prospective Multicenter Study." Ultraschall in der Medizin 36.6 (2015): 590-3.

BibTeX: Download