Towards the synthesis of an Mg-containing silicate glass-ceramic to be used as a scaffold for cementum/alveolar bone regeneration

Goudouri OM, Kontonasaki E, Chrissafis K, Zinn K, Hoppe A, Detsch R, Paraskevopoulos KM, Boccaccini AR (2014)

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2014

Journal

Ceramics International Elsevier

Publisher: Elsevier

Book Volume: 40

Pages Range: 16287-16298

Journal Issue: 10, Part B

DOI: 10.1016/j.ceramint.2014.07.066

Abstract

The gradual destruction of periodontal tissue and in particular the reduction of alveolar bone height which can ultimately lead to tooth loss is a common problem in patients suffering from periodontal disease. The aim of the present work was to investigate the sol-gel synthesis and characterization of a family of new Mg-containing bioactive silicate glasses for applications in cementum/alveolar bone regeneration. Their microstructural, biological and mechanical characteristics were optimized for the fabrication of functional bioceramic scaffolds using the foam replica technique. The optimal glass composition for periodontal tissue replacement was found to contain 60 mol% SiO, 30 mol% CaO and 10 mol% MgO. After sintering, this composition had enhanced mechanical properties combined with the desired apatite-forming ability, which was tested in simulated body fluid (SBF) for up to 5 days. In vitro analysis revealed positive effects of these scaffolds on bone marrow stromal cells.

Authors with CRIS profile

Ourania Menti Goudouri Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Alexander Hoppe Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Rainer Detsch Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Aristotle University of Thessaloniki GR Greece (GR)

How to cite

APA:

Goudouri, O.M., Kontonasaki, E., Chrissafis, K., Zinn, K., Hoppe, A., Detsch, R.,... Boccaccini, A.R. (2014). Towards the synthesis of an Mg-containing silicate glass-ceramic to be used as a scaffold for cementum/alveolar bone regeneration. Ceramics International, 40(10, Part B), 16287-16298. https://doi.org/10.1016/j.ceramint.2014.07.066

MLA:

Goudouri, Ourania Menti, et al. "Towards the synthesis of an Mg-containing silicate glass-ceramic to be used as a scaffold for cementum/alveolar bone regeneration." Ceramics International 40.10, Part B (2014): 16287-16298.

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