Synthesis of substituted cycloalkene-1,1-dicarboxylates via olefin metathesis in water
Tenbrink K, Kemker I, Schatz J, Gröger H (2014)
Publication Status: Published
Publication Type: Journal article, Original article
Publication year: 2014
Journal
Publisher: Arkat USA Inc
Book Volume: 2015
Pages Range: 10-19
Journal Issue: 2
DOI: 10.3998/ark.5550190.p008.812
Abstract
A range of substituted cycloalkene-1,1-dicarboxylates was synthesized through olefin metathesis starting from readily available acylic malonate precursors in an efficient fashion. As a metathesis catalyst, a Grubbs II-type catalyst was used in these experiments, which were run in water and gave the cyclic malonate products with high conversions of 94-100%. The catalytic amount was in the range of 0.5-5 mol% dependent on the structure of the starting material. The generality of this metathesis reaction in water was demonstrated as well as its suitability for the preparation of five and six-membered and alkyl as well as aryl-substituted prochiral cycloalkene-1,1-dicarboxylates.
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Germany (DE)How to cite
APA:
Tenbrink, K., Kemker, I., Schatz, J., & Gröger, H. (2014). Synthesis of substituted cycloalkene-1,1-dicarboxylates via olefin metathesis in water. Arkivoc, 2015(2), 10-19. https://doi.org/10.3998/ark.5550190.p008.812
MLA:
Tenbrink, Katharina, et al. "Synthesis of substituted cycloalkene-1,1-dicarboxylates via olefin metathesis in water." Arkivoc 2015.2 (2014): 10-19.
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